Snap25 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSnap25 ELISA Kit for Rat(Rattus norvegicus)

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Snap25 (Gene name),

Synaptosomal-associated protein 25 (Protein name ), SNP25_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Snap25(Snap);

Protein name:

Synaptosomal-associated protein 25(SNAP-25);

Alternative:

Synaptosomal-associated 25 kDa protein;Super protein(SUP);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with CENP and OTOF. Found in a complex containing SYT1, SV2B and syntaxin-1 (By similarity). Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with TRIM9, RIMS1, SNAPIN, and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8.

Function:

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.

Subcellular Location:

Cytoplasm perinuclear region Cell membrane Lipid-anchor Cell junction synapse synaptosome Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region.

Protein Attributes:

Sequence length:

206

Sequence:

50:

100:

150:

200:

206:

KMLGSG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00835

String:

P60881

SMR:

P60881

KEGG:

rno:25012

UniGene:

Rn.107689

Uniprot:

P60881

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ELISA Kit for Rat SNAP-25

Cat.:

E15057h

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96T

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ELISA Kit for Rat SNAP-25

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ELISA Kit for Rat SNAP-25

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ELISA Kit for Rat SNAP-25

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ELISA Kit for Rat SNAP-25

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ELISA Kit for Rat SNAP-25

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CLIA Kit for Rat SNAP-25

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CLIA Kit for Rat SNAP-25

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CLIA Kit for Rat SNAP-25

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CLIA Kit for Rat SNAP-25

MSDS:

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CLIA Kit for Rat SNAP-25

MSDS:

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CLIA Kit for Rat SNAP-25

Cat.:

U15057h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat SNAP-25

Monoclonal Antibody for Rat SNAP-25

Protein for Rat SNAP-25

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

Kataoka M.
Submitted (1997-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
2.

"Cloning of the SNAP-25 gene from a rat brain cDNA library."
Cho A.R. , You K.H.
Submitted (2000-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
4.

"SNARE complex proteins, including the cognate pair VAMP-2 and syntaxin-4, are expressed in cultured oligodendrocytes."
Madison D.L. , Krueger W.H. , Cheng D. , Trapp B.D. , Pfeiffer S.E.
J. Neurochem.72:988-998(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 10-190 (ISOFORM 1)
tissue: Brain.
5.

Lubec G. , Afjehi-Sadat L. , Diao W. , Kang S.U. , Lubec S.
Submitted (2007-09) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 46-69; 84-94; 104-119; 125-136 AND 143-161;IDENTIFICATION BY MASS SPECTROMETRY
strain: Sprague-Dawley.
tissue: Brain.
tissue: Hippocampus.
tissue: Spinal cord.
6.

"The 25 kDa synaptosomal-associated protein SNAP-25 is the major methionine-rich polypeptide in rapid axonal transport and a major substrate for palmitoylation in adult CNS."
Hess D.T. , Slater T.M. , Wilson M.C. , Skene J.H.P.
J. Neurosci.12:4634-4641(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION;SUBCELLULAR LOCATION
7.

"Differential phosphorylation of SNAP-25 in vivo by protein kinase C and protein kinase A."
Hepp R. , Cabaniols J.-P. , Roche P.A.
FEBS Lett.532:52-56(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT THR-138 AND SER-187
8.

"Differential subcellular localization of SNAP-25a and SNAP-25b RNA transcripts in spinal motoneurons and plasticity in expression after nerve injury."
Jacobsson G. , Piehl F. , Bark I.C. , Zhang X. , Meister B.
Brain Res. Mol. Brain Res.37:49-62(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION OF RNA TRANSCRIPTS
9.

"Hrs-2 is an ATPase implicated in calcium-regulated secretion."
Bean A.J. , Seifert R. , Chen Y.A. , Sacks R. , Scheller R.H.
Nature385:826-829(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HGS
10.

"Mixed and non-cognate SNARE complexes. Characterization of assembly and biophysical properties."
Fasshauer D. , Antonin W. , Margittai M. , Pabst S. , Jahn R.
J. Biol. Chem.274:15440-15446(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A TERNARY COMPLEX WITH STX1A AND VAMP8
11.

"Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin."
Coppola T. , Magnin-Luethi S. , Perret-Menoud V. , Gattesco S. , Schiavo G. , Regazzi R.
J. Biol. Chem.276:32756-32762(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RIMS1
12.

"Amisyn, a novel syntaxin-binding protein that may regulate SNARE complex assembly."
Scales S.J. , Hesser B.A. , Masuda E.S. , Scheller R.H.
J. Biol. Chem.277:28271-28279(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STXBP6
13.

"Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution."
Sutton R.B. , Fasshauer D. , Jahn R. , Brunger A.T.
Nature395:347-353(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 1-83 AND 120-206 IN COMPLEX WITH STX1A AND VAMP2
14.

"Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a."
Misura K.M.S. , Gonzalez L.C. Jr. , May A.P. , Scheller R.H. , Weis W.I.
J. Biol. Chem.276:41301-41309(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 1-83 IN COMPLEX WITH STX1A
15.

"High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex."
Ernst J.A. , Brunger A.T.
J. Biol. Chem.278:8630-8636(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.45 ANGSTROMS) OF 7-83 AND 141-204 IN COMPLEX WITH STX1A AND VAMP2

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